Getting Started With Treatment


INVEGA TRINZA® is gradually released in your body. One dose, given by injection from a healthcare professional, is proven to help control schizophrenia symptoms for 3 months, so it only has to be taken four times a year. If you and your doctor decide that INVEGA TRINZA® is right for you, here is how your treatment plan might look:


Starting Doses

Your doctor may give you an oral test dose to determine if you are allergic to any of the ingredients in INVEGA TRINZA®. Then you will receive your first starting dose of INVEGA SUSTENNA®, followed by a second starting dose one week later. Starting doses are not necessary if you are currently taking INVEGA SUSTENNA®.


You will get injections of INVEGA SUSTENNA® (paliperidone palmitate) for a minimum of four months in a row (including starting doses) until your doctor determines the right dose for you.


When your doctor tells you it is time, you will be transitioned to the appropriate dose of INVEGA TRINZA®. You will then get a dose of INVEGA TRINZA® once every 3 months.



The most common side effects of INVEGA TRINZA® include injection site reactions, weight gain, headache, upper respiratory tract infections, feeling restlessness or difficulty sitting still, slow movements, tremors, stiffness and shuffling walk. Tell your healthcare provider if you have any side effect that bothers you or does not go away.

The most common side effects of INVEGA SUSTENNA® include injection site reactions; sleepiness or drowsiness; dizziness; feeling of inner restlessness or needing to be constantly moving; abnormal muscle movements, including tremor (shaking), shuffling, uncontrolled involuntary movements, and abnormal movements of your eyes.

Please see the Patient Information Pamphlet for full prescribing information.